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| Time/TV | Thursday September 25, 2025 | Line | Money Line | OU | Location |
|---|---|---|---|---|---|
8:15 PM ET PRIME |  Seattle Seahawks Arizona Cardinals | +2.5 -2.5 | +110 -130 | 46.5 | State Farm Stadium glendale , AZ |
| Time/TV | Sunday September 28, 2025 | Line | Money Line | OU | Location |
9:30 AM ET NFL |  Minnesota Vikings Pittsburgh Steelers | -1.5 +1.5 | -122 +102 | 42.5 | Croke Park dublin , ireland |
1:00 PM ET CBS |  New Orleans Saints Buffalo Bills | +12.5 -12.5 | +440 -600 | 46.5 | Highmark Stadium buffalo , NY |
1:00 PM ET FOX |  Carolina Panthers New England Patriots | +3.5 -3.5 | +145 -175 | 45.5 | Gillette Stadium foxboro , MA |
1:00 PM ET CBS |  Tennessee Titans Houston Texans | +6 -6 | +195 -238 | 44.5 | NRG Stadium houston , TX |
1:00 PM ET CBS |  Los Angeles Chargers New York Giants | -3.5 +3.5 | -175 +145 | 43.5 | Metlife Stadium east rutherford , NJ |
1:00 PM ET FOX |  Cleveland Browns Detroit Lions | +10.5 -10.5 | +380 -500 | 45.5 | Ford Field detroit , MI |
1:00 PM ET CBS |  Wash Commanders Atlanta Falcons | -3.5 +3.5 | -175 +145 | 48.5 | Mercedes-Benz Stadium atlanta , GA |
1:00 PM ET FOX |  Philadelphia Eagles Tampa Bay Buccaneers | -2.5 +2.5 | -130 +110 | 48.5 | Raymond James Stadium tampa , FL |
4:05 PM ET FOX |  Jacksonville Jaguars San Francisco 49ers | +5.5 -5.5 | +180 -218 | 48.5 | Levis Stadium santa clara , CA |
4:05 PM ET FOX |  Indianapolis Colts Los Angeles Rams | +6.5 -6.5 | +235 -290 | 46.5 | SoFi Stadium los angeles , CA |
4:25 PM ET CBS |  Baltimore Ravens Kansas City Chiefs | +1.5 -1.5 | +100 -120 | 48.5 | Geha Field at Arrowhead Stadium kansas city , MO |
4:25 PM ET CBS |  Chicago Bears Las Vegas Raiders | -1.5 +1.5 | -120 +100 | 45.5 | Allegiant Stadium las vegas , NV |
8:20 PM ET NBC |  Green Bay Packers Dallas Cowboys | -1.5 +1.5 | -122 +102 | 47.5 | AT&T Stadium arlington , TX |
| Time/TV | Monday September 29, 2025 | Line | Money Line | OU | Location |
7:15 PM ET ESPN |  New York Jets Miami Dolphins | +5.5 -5.5 | +185 -225 | 44.5 | Hard Rock Stadium miami , FL |
8:15 PM ET ABC |  Cincinnati Bengals Denver Broncos | +2.5 -2.5 | +110 -130 | 47.5 | Empower Field At Mile High denver , CO |
Active Betting Splits| League | Events |
|---|---|
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| League | Events |
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 UFC | 31 |
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