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Levis Stadium

FINAL	Score	Line	OU	Record	ATS	O-U-P	PF	PA	EST Score	EST Line
Cardinals	15	+1.5		2-0	1-1-0	1-1-0	23.5	17.5	18.1	40.7
49ers	16	-1.5	44.5	2-0	2-0-0	1-1-0	21.5	17.0	22.6	-4.5

DraftKings Betting Splits

Sunday,Sep 21	Spread	Handle	Bets	Total	Handle	Bets	Money	Handle	Bets
Arizona Cardinals San Francisco 49ers	+1.5 -1.5	36% 64%	42% 58%	44.5 44.5	69% 31%	64% 36%	+105 -125	48% 52%	39% 61%

Circa Sports Betting Splits

Sunday,Sep 21	Spread	Handle	Bets	Total	Handle	Bets	Money	Handle	Bets
Arizona Cardinals San Francisco 49ers	+1.5 -1.5	63% 37%	29% 71%	44.5 44.5	54% 46%	46% 54%	102 -122	42% 58%	45% 55%

Pro Picks at a Glance

VSiN Expert	Sport	Event Date	Selection	Score	Result
Zachary Cohen	NFL	2025-09-21	Christian Mccaffrey (49ers) OVER 68.5 Rushing Yards (-112)	52	LOSS
Scott Seidenberg	NFL	2025-09-21	49ers (-2.5) (-105) vs Cardinals	16 - 15	LOSS
Ryan Kramer	NFL	2025-09-21	Cardinals (+2.5) (-115) at 49ers	15 - 16	WIN
Weston Stradtman	NFL	2025-09-21	49ers (-2.5) vs Cardinals	16 - 15	LOSS
Jeff Whitelaw	NFL	2025-09-21	49ers (-2.5) vs Cardinals	16 - 15	LOSS
Weston Stradtman	NFL	2025-09-21	Cardinals at 49ers - UNDER (46.5)	31	WIN
Mike North	NFL	2025-09-21	Cardinals (+2.5) at 49ers	15 - 16	WIN
Jason Jarvis	NFL	2025-09-21	Cardinals (+2.5) at 49ers	15 - 16	WIN
Zachary Cohen	NFL	2025-09-21	Money Line - 49ers (-137) vs Cardinals	16 - 15	WIN
Jensen Lewis	NFL	2025-09-21	Cardinals at 49ers - UNDER (44) (-110)	31	WIN
Dustin Swedelson	NFL	2025-09-21	Cardinals (+1.5) (-110) at 49ers	15 - 16	WIN
Mitch Moss	NFL	2025-09-21	Money Line - 49ers (-120) vs Cardinals	16 - 15	WIN
Stormy Buonantony	NFL	2025-09-21	49ers (-2.5) (-110) vs Cardinals	16 - 15	LOSS

Makinen Weekly Ratings

Sunday, September 21	Score	Line	OU	PR	Line	Score	Proj	Score	Proj
		DraftKings			Power Ratings		Effective Strength		Bettor Rating
Arizona Cardinals	15	+1.5		24.0		18.1	40.7	20.5	42.1
San Francisco 49ers	16	-1.5	44.5	26.0	0.1	22.6	-4.5	21.7	-1.2

2025 Recent Results

Wk	Date	Opponent	ML	Line	OU	Score	SU	ATS	OU	Handle	Bets	Handle	Bets	Handle	Bets
Arizona			DraftKings			Results				Money Line		Spread		OVER Total
2	Sep 14	VS Carolina	-310	-7	45.5	27-22	W	L	O	88%	94%	66%	68%	86%	46%
1	Sep 7	at New Orleans	-278	-6	44.5	20-13	W	W	U	83%	90%	81%	74%	75%	51%

2025 Recent Results

Wk	Date	Opponent	ML	Line	OU	Score	SU	ATS	OU	Handle	Bets	Handle	Bets	Handle	Bets
San Francisco			DraftKings			Results				Money Line		Spread		OVER Total
2	Sep 14	at New Orleans	-166	-3	40.5	26-21	W	W	O	66%	80%	69%	72%	53%	46%
1	Sep 7	at Seattle	-135	-2.5	43.5	17-13	W	W	U	62%	71%	64%	65%	64%	59%

Last 5 Head to Head Results

Date	Road/Home	Score	Line	ML	OU	SU	ATS	F/D	H/A	OU
2025 Jan 5	San Francisco 49ers Arizona Cardinals	24 47	+5.5 -5.5	+185 -225	43.5	ARI	ARI	FAV	Home	Over
2024 Oct 6	Arizona Cardinals San Francisco 49ers	24 23	+7.5 -7.5	+270 -340	49	ARI	ARI	DOG	Road	Under
2023 Dec 17	San Francisco 49ers Arizona Cardinals	45 29	-11.5 +11.5	-700 +500	48.5	SFO	SFO	FAV	Road	Over
2023 Oct 1	Arizona Cardinals San Francisco 49ers	16 35	+15 -15	+700 -1100	44	SFO	SFO	FAV	HOME	Over
2023 Jan 8	Arizona Cardinals San Francisco 49ers	13 38	+14.5 -14.5	+700 -1050	40	SFO	SFO	FAV	HOME	Over

Statistic Breakdown

Offensive Statistics

ARI	Statistic	SFO	Edge	Margin
2	Games	2	-	0
23.5	Points Scored	21.5	ARI	2.0
170.5	Passing Yards	266.0	SFO	95.5
9.0	PYPC	10.2	SFO	1.3
6.3	PYPA	7.2	SFO	0.9
70.4	Completion PCT	70.3	ARI	0.1
114.0	Rushing Yards	98.0	ARI	16.0
4.7	RYPA	3.2	ARI	1.5
75.0	PenaltyYards	50.5	SFO	24.5
0.5	Turnovers	1.5	ARI	1.0

Defensive Statistics

ARI	Statistic	SFO	Edge	Margin
2	Games	2	-	0
17.5	Points Scored	17.0	SFO	0.5
255.5	Passing Yards	166.0	SFO	89.5
8.2	PYPC	8.1	SFO	0.1
5.1	PYPA	5.8	ARI	0.8
61.4	Completion PCT	71.9	ARI	10.5
78.0	Rushing Yards	102.5	ARI	24.5
3.8	RYPA	3.7	SFO	0.1
86.0	PenaltyYards	37.5	ARI	48.5
1.0	Turnovers	1.5	SFO	0.5

Statistic Breakdown

Offensive Statistics

ARI	Statistic	SFO	Edge	Margin
1	Games	0	ARI	1
20.0	Points Scored	0.0	ARI	20.0
130.0	Passing Yards	0.0	ARI	130.0
6.2	PYPC	0.0	ARI	6.2
4.5	PYPA	0.0	ARI	4.5
72.4	Completion PCT	0.0	ARI	72.4
146.0	Rushing Yards	0.0	ARI	146.0
5.4	RYPA	0.0	ARI	5.4
54.0	PenaltyYards	0.0	SFO	54.0
0.0	Turnovers	0.0	-	0.0

Defensive Statistics

ARI	Statistic	SFO	Edge	Margin
1	Games	0	SFO	1
13.0	Points Scored	0.0	SFO	13.0
208.0	Passing Yards	0.0	SFO	208.0
7.7	PYPC	0.0	SFO	7.7
4.5	PYPA	0.0	SFO	4.5
58.7	Completion PCT	0.0	SFO	58.7
107.0	Rushing Yards	0.0	SFO	107.0
4.9	RYPA	0.0	SFO	4.9
89.0	PenaltyYards	0.0	ARI	89.0
0.0	Turnovers	0.0	-	0.0

Statistic Breakdown

Offensive Statistics

ARI	Statistic	SFO	Edge	Margin
10	Games	10	-	0
24.0	Points Scored	19.9	ARI	4.1
226.9	Passing Yards	240.1	SFO	13.2
9.3	PYPC	10.9	SFO	1.6
6.6	PYPA	7.3	SFO	0.7
70.4	Completion PCT	66.9	ARI	3.6
133.2	Rushing Yards	101.2	ARI	32.0
5.1	RYPA	4.1	ARI	1.1
59.7	PenaltyYards	50.3	SFO	9.4
1.0	Turnovers	1.8	ARI	0.8

Defensive Statistics

ARI	Statistic	SFO	Edge	Margin
10	Games	10	-	0
20.0	Points Scored	26.8	ARI	6.8
212.8	Passing Yards	183.3	SFO	29.5
9.1	PYPC	9.2	ARI	0.0
6.1	PYPA	6.5	ARI	0.4
66.2	Completion PCT	70.4	ARI	4.2
110.9	Rushing Yards	136.7	ARI	25.8
4.6	RYPA	4.4	SFO	0.2
60.6	PenaltyYards	34.7	ARI	25.9
0.9	Turnovers	0.5	ARI	0.4

Statistic Breakdown

Offensive Statistics

ARI	Statistic	SFO	Edge	Margin
47	Games	47	-	0
21.2	Points Scored	23.7	SFO	2.5
237.3	Passing Yards	221.6	ARI	15.7
10.4	PYPC	11.1	SFO	0.6
6.4	PYPA	6.7	SFO	0.3
61.4	Completion PCT	60.8	ARI	0.7
103.5	Rushing Yards	118.8	SFO	15.3
4.0	RYPA	4.3	SFO	0.3
50.6	PenaltyYards	52.0	ARI	1.5
1.8	Turnovers	1.4	SFO	0.4

Player	Pos	Injury
Cardinals

Player	Position	Injury
49ers

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