Highmark Stadium

    FINAL
    ScoreLineOURecordATSO-U-PPFPAEST ScoreEST Line
     Saints
    19
    +15.5
    0-30-3-02-1-015.730.0
    17.9
    49.7
     Bills
    31
    -15.5
    48.5
    3-02-1-02-1-034.023.7
    31.8
    -13.9


    DraftKings Betting Splits
    Sunday,Sep 28SpreadHandleBetsTotalHandleBetsMoneyHandleBets
     New Orleans Saints
     Buffalo Bills

    51%  

    49%
    27%

    73%

    77%  

    23%
    56%

    44%

    8%

    92%
    3%

    97%
    Circa Sports Betting Splits
    Sunday,Sep 28SpreadHandleBetsTotalHandleBetsMoneyHandleBets
     New Orleans Saints
     Buffalo Bills
    +14.5

    -14.5
    73%

    27%
    26%

    74%
    49

    49
    98%

    2%
    53%

    47%  
    875

    -1400
    86%

    14%
    74%

    26%  

    Pro Picks at a Glance
    VSiN ExpertSportEvent DateSelectionScoreResult
    Wes Reynolds
     NFL2025-09-28Alvin Kamara (Saints) UNDER 14.5 Rushing Attempts (-130)
    15
    LOSS
    Stormy Buonantony
     NFL2025-09-281Q - Bills (-3.5) vs Saints
    14 - 7
    WIN
    Wes Reynolds
     NFL2025-09-28Saints (+16) (-110) at Bills
    19 - 31
    WIN
    Matt Youmans
     NFL2025-09-28Saints (+15.5) (-110) at Bills
    19 - 31
    WIN
    Zachary Cohen
     NFL2025-09-28Spencer Rattler (Saints) OVER 200.5 Passing Yards (-114) [ 1.5 units ]
    126
    LOSS
    Zachary Cohen
     NFL2025-09-28Spencer Rattler (Saints) OVER 1.5 Passing TD (+275) [ 0.5 units ]
    1
    LOSS
    Jensen Lewis
     NFL2025-09-28Juwan Johnson (Saints) OVER 4.5 Receptions (-125) [ 0.5 units ]
    3
    LOSS
    Tony Gordon
     NFL2025-09-28Saints (+15.5) at Bills
    19 - 31
    WIN
    Cris Zeniuk
     NFL2025-09-28Saints (+15.5) at Bills
    19 - 31
    WIN
    Ryan Kramer
     NFL2025-09-28Saints (+15.5) (-108) at Bills
    19 - 31
    WIN
    Jason Jarvis
     NFL2025-09-28Saints (+15.5) at Bills
    19 - 31
    WIN
    Makinen Weekly Ratings
    DraftKingsPower RatingsEffective StrengthBettor Rating
     Sunday, September 28ScoreLineOUPRLineScoreProjEdgeScoreProjEdge
    New Orleans Saints New Orleans Saints
    19
    +15.5
    15.5
    17.9
    49.7
    18.0
    48.7
    Buffalo Bills Buffalo Bills
    31
    -15.5
    48.5
    30.5
    -17.8
    31.8
    -13.9
    30.8
    -12.8


    2025 Recent Results
    New OrleansDraftKingsResultsMoney LineSpreadOVER Total
    WkDateOpponentMLLineOUScoreSUATSOUHandleBetsHandleBetsHandleBets
    Sep 21 at  Seattle
    +295
    +7.5
    41.5
    13-44
    L
    L
    O
    8%
    4%
    48%
    34%
    83%
    54%
    Sep 14 VS  San Francisco
    +140
    +3
    40.5
    21-26
    L
    L
    O
    34%
    20%
    31%
    28%
    53%
    46%
    Sep 7 VS  Arizona
    +225
    +6
    44.5
    13-20
    L
    L
    U
    17%
    10%
    19%
    26%
    75%
    51%

    2025 Recent Results
    BuffaloDraftKingsResultsMoney LineSpreadOVER Total
    WkDateOpponentMLLineOUScoreSUATSOUHandleBetsHandleBetsHandleBets
    Sep 18 VS  Miami
    -850
    -12.5
    50.5
    31-21
    W
    L
    O
    75%
    90%
    51%
    68%
    75%
    66%
    Sep 14 at  NY Jets
    -290
    -6
    47.5
    30-10
    W
    W
    U
    80%
    94%
    37%
    70%
    81%
    78%
    Sep 7 VS  Baltimore
    +105
    +1.5
    51.5
    41-40
    W
    W
    O
    40%
    49%
    49%
    49%
    56%
    63%

    Last 5 Head to Head Results
    DateRoad/HomeScoreLineMLOUSUATSF/DH/AOU

    2021
    Nov 25
    Buffalo Bills Buffalo Bills
    New Orleans Saints New Orleans Saints
    31


    6
    -7


    +7
    -305


    +240
    44.5
    BUF

     
    BUF

     
    FAV
    Road

     
    Under

    2017
    Nov 12
    New Orleans Saints New Orleans Saints
    Buffalo Bills Buffalo Bills
    47


    10
    -2.5


    +2.5
    -135


    +115
    48
    NOR

     
    NOR

     
    FAV
    Road

     
    Over

    2013
    Oct 27
    Buffalo Bills Buffalo Bills
    New Orleans Saints New Orleans Saints
    17


    35
    +10


    -10
    +395


    -510
    48
    NOR

     
    NOR

     
    FAV
    Home

     
    Over

    2009
    Sep 27
    New Orleans Saints New Orleans Saints
    Buffalo Bills Buffalo Bills
    27


    7
    -5.5


    +5.5
    -225


    +210
    51
    NOR

     
    NOR

     
    FAV
    Road

     
    Under

    2005
    Oct 2
    Buffalo Bills Buffalo Bills
    New Orleans Saints New Orleans Saints
    7


    19
    +1.5


    -1.5
    -


    -
    39.5
    NOR

     
    NOR

     
    FAV
    Home

     
    Under



    Statistic Breakdown
    Offensive Statistics
    NOR NORStatisticBUF BUFEdgeMargin
    3
    Games
    3
    -
    0
    15.7
    Points Scored
    34.0
    BUF BUF
    18.3
    199.7
    Passing Yards
    257.0
    BUF BUF
    57.3
    7.5
    PYPC
    11.0
    BUF BUF
    3.5
    5.0
    PYPA
    7.6
    BUF BUF
    2.7
    66.1
    Completion PCT
    69.3
    BUF BUF
    3.2
    102.3
    Rushing Yards
    163.0
    BUF BUF
    60.7
    3.9
    RYPA
    4.8
    BUF BUF
    1.0
    70.3
    PenaltyYards
    47.3
    BUF BUF
    23.0
    0.7
    Turnovers
    0.0
    BUF BUF
    0.7
    Defensive Statistics
    NOR NORStatisticBUF BUFEdgeMargin
    3
    Games
    3
    -
    0
    30.0
    Points Scored
    23.7
    BUF BUF
    6.3
    210.0
    Passing Yards
    131.3
    BUF BUF
    78.7
    10.0
    PYPC
    8.6
    BUF BUF
    1.4
    7.1
    PYPA
    5.3
    BUF BUF
    1.8
    70.8
    Completion PCT
    61.3
    BUF BUF
    9.5
    103.3
    Rushing Yards
    156.0
    NOR NOR
    52.7
    3.6
    RYPA
    6.2
    NOR NOR
    2.6
    54.7
    PenaltyYards
    47.7
    NOR NOR
    7.0
    0.7
    Turnovers
    1.0
    BUF BUF
    0.3

    Statistic Breakdown
    Offensive Statistics
    NOR NORStatisticBUF BUFEdgeMargin
    1
    Games
    2
    BUF BUF
    1
    13.0
    Points Scored
    36.0
    BUF BUF
    23.0
    205.0
    Passing Yards
    296.0
    BUF BUF
    91.0
    7.3
    PYPC
    10.8
    BUF BUF
    3.4
    5.0
    PYPA
    8.0
    BUF BUF
    3.0
    68.3
    Completion PCT
    74.3
    BUF BUF
    6.0
    79.0
    Rushing Yards
    132.5
    BUF BUF
    53.5
    2.9
    RYPA
    4.6
    BUF BUF
    1.6
    77.0
    PenaltyYards
    36.5
    BUF BUF
    40.5
    1.0
    Turnovers
    0.0
    BUF BUF
    1.0
    Defensive Statistics
    NOR NORStatisticBUF BUFEdgeMargin
    1
    Games
    2
    NOR NOR
    1
    44.0
    Points Scored
    30.5
    BUF BUF
    13.5
    233.0
    Passing Yards
    170.0
    BUF BUF
    63.0
    14.6
    PYPC
    9.4
    BUF BUF
    5.1
    11.1
    PYPA
    6.4
    BUF BUF
    4.7
    76.2
    Completion PCT
    67.9
    BUF BUF
    8.3
    87.0
    Rushing Yards
    184.0
    NOR NOR
    97.0
    2.6
    RYPA
    6.8
    NOR NOR
    4.2
    70.0
    PenaltyYards
    54.0
    NOR NOR
    16.0
    1.0
    Turnovers
    1.0
    -
    0.0

    Statistic Breakdown
    Offensive Statistics
    NOR NORStatisticBUF BUFEdgeMargin
    10
    Games
    10
    -
    0
    15.8
    Points Scored
    31.7
    BUF BUF
    15.9
    196.3
    Passing Yards
    227.9
    BUF BUF
    31.6
    8.8
    PYPC
    11.3
    BUF BUF
    2.4
    5.5
    PYPA
    7.5
    BUF BUF
    2.0
    62.0
    Completion PCT
    66.0
    BUF BUF
    4.0
    103.7
    Rushing Yards
    158.9
    BUF BUF
    55.2
    4.3
    RYPA
    4.7
    BUF BUF
    0.3
    56.8
    PenaltyYards
    46.7
    BUF BUF
    10.1
    1.0
    Turnovers
    0.1
    BUF BUF
    0.9
    Defensive Statistics
    NOR NORStatisticBUF BUFEdgeMargin
    10
    Games
    10
    -
    0
    24.2
    Points Scored
    23.5
    BUF BUF
    0.7
    223.9
    Passing Yards
    213.9
    BUF BUF
    10.0
    10.6
    PYPC
    10.6
    NOR NOR
    0.0
    6.6
    PYPA
    7.0
    NOR NOR
    0.4
    62.6
    Completion PCT
    65.7
    NOR NOR
    3.1
    130.4
    Rushing Yards
    122.1
    BUF BUF
    8.3
    4.3
    RYPA
    4.8
    NOR NOR
    0.5
    57.4
    PenaltyYards
    48.8
    NOR NOR
    8.6
    0.4
    Turnovers
    1.5
    BUF BUF
    1.1

    Statistic Breakdown
    Offensive Statistics
    NOR NORStatisticBUF BUFEdgeMargin
    6
    Games
    6
    -
    0
    26.3
    Points Scored
    13.0
    NOR NOR
    13.3
    192.2
    Passing Yards
    155.8
    NOR NOR
    36.3
    10.5
    PYPC
    8.7
    NOR NOR
    1.8
    6.6
    PYPA
    5.2
    NOR NOR
    1.4
    63.2
    Completion PCT
    60.0
    NOR NOR
    3.2
    152.8
    Rushing Yards
    104.2
    NOR NOR
    48.7
    4.5
    RYPA
    4.3
    NOR NOR
    0.2
    47.0
    PenaltyYards
    61.0
    NOR NOR
    14.0
    0.5
    Turnovers
    2.2
    NOR NOR
    1.7

     Saints
    PlayerPosInjury
    Chase Young
    DE
    Calf - is Questionable Sunday vs NY Giants
    Cesar Ruiz
    C
    Ankle - left last game, is Questionable Sunday vs NY Giants
    Dillon Radunz
    OL
    Toe - is Questionable Sunday vs NY Giants
    Trey Palmer
    WR
    Hamstring - is Questionable Sunday vs NY Giants
    Devaughn Vele
    WR
    Hip - is upgraded to probable Sunday vs Buffalo
    Taliese Fuaga
    T
    Knee - is upgraded to probable Sunday vs Buffalo
    Justin Reid
    S
    Head - is upgraded to probable Sunday vs Buffalo
    Trevor Penning
    T
    Toe - is upgraded to probable Sunday vs Seattle
    Devaughn Vele
    WR
    Hip - is Questionable Sunday vs Seattle
    Julian Blackmon
    S
    Shoulder - IR
    Mason Pline
    TE
    Upper Body - is out for season
    Nick Saldiveri
    OL
    Knee - is out for season
    Landon Young
    T
    Undisclosed - is out for season
    Bub Means
    WR
    Leg - is out for season
    Will Clapp
    C
    Foot - is out for season
    Barry Wesley
    -
    Undisclosed - IR; will miss at least the first 4 games of season
    John Ridgeway
    DT
    Pectoral - IR; will miss at least the first 4 games of season
    Foster Moreau
    TE
    Knee - IR; will miss at least the first 4 games of season
    Taysom Hill
    QB
    Knee - IR; will miss at least the first 4 games of season
     Bills
    PlayerPositionInjury
    Matt Milano
    LB
    Pectoral - is Questionable Sunday vs New England
    Ed Oliver
    DT
    Ankle - is Questionable Sunday vs New England
    Spencer Brown
    T
    Calf - is Questionable Sunday vs New England
    AJ Epenesa
    DE
    Pectoral - is upgraded to probable Sunday vs New Orleans
    Jordan Hancock
    DB
    Shoulder - is upgraded to probable Sunday vs New Orleans
    Shaq Thompson
    LB
    Hamstring - is upgraded to probable Thursday vs Miami
    Cam Lewis
    CB
    Shoulder - is upgraded to probable Thursday vs Miami
    Taron Johnson
    CB
    Quad - is upgraded to probable Thursday vs Miami
    Tyler Bass
    K
    Hip - IR; is out at least first 4 games of season
    Maxwell Hairston
    CB
    Knee - IR; is out at least first 4 games of season
    DeWayne Carter
    DT
    Achilles - is out for season
    Michael Hoecht
    DE
    Suspension - is OUT the first 6 games of the season
    Larry Ogunjobi
    DT
    Suspension - is OUT for the first 6 games of the season