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State Farm Stadium

FINAL	Score	Line	OU	Record	ATS	O-U-P	PF	PA	EST Score	EST Line
49ers	41	-3.5		6-4	5-5-0	6-4-0	22.0	23.0	25.7	48.3
Cardinals	22	+3.5	48.5	3-6	5-4-0	5-4-0	22.4	23.9	22.6	3.2

DraftKings Betting Splits

Sunday,Nov 16	Spread	Handle	Bets	Total	Handle	Bets	Money	Handle	Bets
San Francisco 49ers Arizona Cardinals	-3.5 +3.5	72% 28%	75% 25%	48.5 48.5	68% 32%	40% 60%	-185 +154	92% 8%	88% 12%

Circa Sports Betting Splits

Sunday,Nov 16	Spread	Handle	Bets	Total	Handle	Bets	Money	Handle	Bets
San Francisco 49ers Arizona Cardinals	-3.5 +3.5	77% 23%	83% 17%	48 48	32% 68%	72% 28%	-195 170	46% 54%	68% 32%

Pro Picks at a Glance

VSiN Expert	Sport	Event Date	Selection	Score	Result
Howard Bender	NFL	2025-11-16	Michael Wilson (Cardinals) OVER 44.5 Receiving Yards (-110)	185	WIN
John Hansen	NFL	2025-11-16	Trey Mcbride (Cardinals) OVER 7.5 Receptions (-101)	10	WIN
Wes Reynolds	NFL	2025-11-16	49ers at Cardinals [LIVE] - OVER (57.5) (-115)	63	WIN
Steve Fezzik	NFL	2025-11-16	Trey Mcbride (Cardinals) OVER 75.5 Receiving Yards (-110)	115	WIN
Pauly Howard	NFL	2025-11-16	Christian Mccaffrey (49ers) OVER 49.5 Receiving Yards (-110)	40	LOSS
Gill Alexander	NFL	2025-11-16	49ers (-2.5) (-130) at Cardinals	41 - 22	WIN
Weston Stradtman	NFL	2025-11-16	49ers (-3) at Cardinals	41 - 22	WIN
Matt Ste. Marie	NFL	2025-11-16	49ers (-3) at Cardinals	41 - 22	WIN
Jeff Erickson	NFL	2025-11-16	Cardinals (+2.5) (-105) vs 49ers	22 - 41	LOSS
Mike North	NFL	2025-11-16	Cardinals (+3) vs 49ers	22 - 41	LOSS
Jeff Petch	NFL	2025-11-16	49ers (-3) at Cardinals	41 - 22	WIN
Drew Bridges	NFL	2025-11-16	49ers (-3) at Cardinals	41 - 22	WIN

Makinen Weekly Ratings

Sunday, November 16	Score	Line	OU	PR	Line	Score	Proj	Score	Proj
		DraftKings			Power Ratings		Effective Strength		Bettor Rating
San Francisco 49ers	41	-3.5		25.5		25.7	48.3	27.6	49.3
Arizona Cardinals	22	+3.5	48.5	22.5	2.5	22.6	3.2	21.8	5.8

2025 Recent Results

Wk	Date	Opponent	ML	Line	OU	Score	SU	ATS	OU	Handle	Bets	Handle	Bets	Handle	Bets
San Francisco			DraftKings			Results				Money Line		Spread		OVER Total
10	Nov 9	VS LA Rams	+210	+5.5	49.5	26-42	L	L	O	32%	22%	40%	48%	52%	53%
9	Nov 2	at NY Giants	-148	-2.5	47.5	34-24	W	W	O	72%	76%	73%	75%	56%	39%
8	Oct 26	at Houston	+130	+2.5	41.5	15-26	L	L	U	42%	77%	29%	71%	82%	67%
7	Oct 19	VS Atlanta	-115	-1.5	46.5	20-10	W	W	U	49%	52%	57%	55%	74%	56%
6	Oct 12	at Tampa Bay	+164	+3.5	47.5	19-30	L	L	O	40%	27%	51%	46%	87%	75%
5	Oct 2	at LA Rams	+350	+7.5	43.5	26-23	W	W	O	20%	16%	43%	43%	60%	50%
4	Sep 28	VS Jacksonville	-180	-3.5	45.5	21-26	L	L	O	57%	78%	25%	54%	60%	35%
3	Sep 21	VS Arizona	-122	-1.5	44.5	16-15	W	L	U	52%	61%	64%	58%	69%	64%
2	Sep 14	at New Orleans	-166	-3	40.5	26-21	W	W	O	66%	80%	69%	72%	53%	46%
1	Sep 7	at Seattle	-135	-2.5	43.5	17-13	W	W	U	62%	71%	64%	65%	64%	59%

2025 Recent Results

Wk	Date	Opponent	ML	Line	OU	Score	SU	ATS	OU	Handle	Bets	Handle	Bets	Handle	Bets
Arizona			DraftKings			Results				Money Line		Spread		OVER Total
10	Nov 9	at Seattle	+285	+7.5	44.5	22-44	L	L	O	16%	9%	38%	36%	39%	70%
9	Nov 3	at Dallas	+145	+3.5	53.5	27-17	W	W	U	10%	14%	34%	19%	74%	64%
7	Oct 19	VS Green Bay	+295	+7	45.5	23-27	L	W	O	36%	9%	42%	32%	78%	69%
6	Oct 12	at Indianapolis	+350	+8.5	46.5	27-31	L	W	O	20%	9%	32%	33%	64%	62%
5	Oct 5	VS Tennessee	-440	-7.5	41.5	21-22	L	L	O	80%	92%	72%	61%	67%	56%
4	Sep 25	VS Seattle	+105	+1.5	43.5	20-23	L	L	U	25%	28%	35%	26%	58%	61%
3	Sep 21	at San Francisco	+102	+1.5	44.5	15-16	L	W	U	48%	39%	36%	42%	69%	64%
2	Sep 14	VS Carolina	-310	-7	45.5	27-22	W	L	O	88%	94%	66%	68%	86%	46%
1	Sep 7	at New Orleans	-278	-6	44.5	20-13	W	W	U	83%	90%	81%	74%	75%	51%

Last 5 Head to Head Results

Date	Road/Home	Score	Line	ML	OU	SU	ATS	F/D	H/A	OU
2025 Sep 21	Arizona Cardinals San Francisco 49ers	15 16	+1.5 -1.5	+102 -122	44.5	SFO	ARI	DOG	Road	Under
2025 Jan 5	San Francisco 49ers Arizona Cardinals	24 47	+5.5 -5.5	+185 -225	43.5	ARI	ARI	FAV	HOME	Over
2024 Oct 6	Arizona Cardinals San Francisco 49ers	24 23	+7.5 -7.5	+270 -340	49	ARI	ARI	DOG	Road	Under
2023 Dec 17	San Francisco 49ers Arizona Cardinals	45 29	-11.5 +11.5	-700 +500	48.5	SFO	SFO	FAV	Road	Over
2023 Oct 1	Arizona Cardinals San Francisco 49ers	16 35	+15 -15	+700 -1100	44	SFO	SFO	FAV	Home	Over

Statistic Breakdown

Offensive Statistics

SFO	Statistic	ARI	Edge	Margin
10	Games	9	SFO	1
22.0	Points Scored	22.4	ARI	0.4
261.4	Passing Yards	202.9	SFO	58.5
10.5	PYPC	8.9	SFO	1.6
7.2	PYPA	5.7	SFO	1.5
68.8	Completion PCT	64.5	SFO	4.3
94.8	Rushing Yards	113.4	ARI	18.6
3.5	RYPA	4.5	ARI	1.0
46.7	PenaltyYards	48.9	SFO	2.2
1.5	Turnovers	1.1	ARI	0.4

Defensive Statistics

SFO	Statistic	ARI	Edge	Margin
10	Games	9	ARI	1
23.0	Points Scored	23.9	SFO	0.9
228.8	Passing Yards	225.3	ARI	3.5
10.0	PYPC	10.0	SFO	0.0
6.8	PYPA	6.4	ARI	0.4
67.9	Completion PCT	64.0	ARI	3.8
110.6	Rushing Yards	114.1	SFO	3.5
4.2	RYPA	4.3	SFO	0.2
38.3	PenaltyYards	62.1	ARI	23.8
0.7	Turnovers	1.4	ARI	0.7

Statistic Breakdown

Offensive Statistics

SFO	Statistic	ARI	Edge	Margin
6	Games	4	SFO	2
22.8	Points Scored	22.8	SFO	0.1
259.5	Passing Yards	200.8	SFO	58.8
10.4	PYPC	8.7	SFO	1.7
7.1	PYPA	6.0	SFO	1.2
68.8	Completion PCT	68.7	SFO	0.2
90.7	Rushing Yards	108.3	ARI	17.6
3.3	RYPA	4.5	ARI	1.2
45.7	PenaltyYards	61.0	SFO	15.3
1.2	Turnovers	1.8	SFO	0.6

Defensive Statistics

SFO	Statistic	ARI	Edge	Margin
6	Games	4	ARI	2
22.8	Points Scored	23.5	SFO	0.7
242.5	Passing Yards	237.3	ARI	5.3
10.3	PYPC	10.2	ARI	0.1
7.3	PYPA	6.4	ARI	0.9
71.4	Completion PCT	62.4	ARI	8.9
110.2	Rushing Yards	94.0	ARI	16.2
4.3	RYPA	3.7	ARI	0.5
36.7	PenaltyYards	71.5	ARI	34.8
1.0	Turnovers	1.3	ARI	0.3

Statistic Breakdown

Offensive Statistics

SFO	Statistic	ARI	Edge	Margin
10	Games	10	-	0
22.0	Points Scored	24.9	ARI	2.9
261.4	Passing Yards	206.8	SFO	54.6
10.5	PYPC	9.0	SFO	1.5
7.2	PYPA	5.9	SFO	1.4
68.8	Completion PCT	65.2	SFO	3.6
94.8	Rushing Yards	117.2	ARI	22.4
3.5	RYPA	4.6	ARI	1.1
46.7	PenaltyYards	44.5	ARI	2.2
1.5	Turnovers	1.0	ARI	0.5

Defensive Statistics

SFO	Statistic	ARI	Edge	Margin
10	Games	10	-	0
23.0	Points Scored	23.9	SFO	0.9
228.8	Passing Yards	232.6	SFO	3.8
10.0	PYPC	10.0	SFO	0.1
6.8	PYPA	6.5	ARI	0.3
67.9	Completion PCT	64.4	ARI	3.4
110.6	Rushing Yards	116.5	SFO	5.9
4.2	RYPA	4.4	SFO	0.2
38.3	PenaltyYards	64.4	ARI	26.1
0.7	Turnovers	1.6	ARI	0.9

Statistic Breakdown

Offensive Statistics

SFO	Statistic	ARI	Edge	Margin
48	Games	48	-	0
23.6	Points Scored	21.1	SFO	2.5
222.9	Passing Yards	235.6	ARI	12.7
11.1	PYPC	10.4	SFO	0.7
6.7	PYPA	6.4	SFO	0.4
60.9	Completion PCT	61.5	ARI	0.6
117.9	Rushing Yards	103.6	SFO	14.3
4.3	RYPA	4.0	SFO	0.3
52.4	PenaltyYards	50.1	ARI	2.3
1.4	Turnovers	1.8	SFO	0.4

Player	Pos	Injury
49ers
Brock Purdy	QB	Toe - is Questionable Sunday vs Arizona
Ricky Pearsall	WR	Knee - is Questionable Sunday vs Arizona
Alfred Collins	DL	Hip - is Questionable Sunday vs Arizona
Mykel Williams	DL	Knee - is out for season
Yetur Gross-Matos	DL	Hamstring - IR
Fred Warner	LB	Ankle - IR; is out for season
Brandon Aiyuk	WR	Knee - IR
Kurtis Rourke	QB	Knee - IR
Jacob Cowing	WR	Hamstring - IR
Nick Bosa	DE	ACL - IR; is out for season
Patrick Taylor Jr	RB	Shoulder - is out for season

Player	Position	Injury
Cardinals
Mack Wilson Sr	LB	Ribs - is Questionable Sunday vs San Francisco
Xavier Weaver	WR	Ankle - is Questionable Sunday vs San Francisco
Dadrion Taylor-Demerson	S	Ankle - is Questionable Sunday vs San Francisco
Darius Robinson	DL	Groin - is Questionable Sunday vs San Francisco
BJ Ojulari	DE	Knee - is Questionable Sunday vs San Francisco
Max Melton	CB	Concussion - is Questionable Sunday vs San Francisco
Bam Knight	RB	Ankle - is Questionable Sunday vs San Francisco
Zay Jones	WR	Achilles - is Questionable Sunday vs San Francisco
Will Johnson	CB	Back - is Questionable Sunday vs San Francisco
Simi Fehoko	WR	Wrist - is Questionable Sunday vs San Francisco
Kyler Murray	QB	Foot - IR
Travis Vokolek	TE	Neck - IR
Blake Gillikin	P	Back - IR
Tip Reiman	TE	Ankle - IR; is out for season
Hayden Conner	OL	Knee - IR
Trey Benson	RB	Knee - IR
James Conner	RB	Knee - IR
LJ Collier	DL	Knee - IR
Joey Blount	S	Neck - IR
Trishton Jackson	WR	Thumb - is out for season
Sean Murphy-Bunting	CB	Knee - is out for season

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