Highmark Stadium

    8:20 PM ET (NBC)
    ScoreLineOURecordATSO-U-PPFPAEST ScoreEST Line
     49ers
    0
    -2
    5-54-6-05-5-025.022.2
    0
    0
     Bills
    0
    +2
    47
    9-27-4-07-4-029.119.5
    0
    0


    DraftKings Betting Splits
    Sunday,December 1SpreadHandleBetsTotalHandleBetsMoneyHandleBets

    15%

    85%
    13%

    87%

    35%

    65%
    57%

    43%

    2%

    98%
    67%

    33%  
    Circa Sports Betting Splits
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    2024 Recent Results
    San FranciscoDraftKingsResultsMoney LineSpreadOVER Total
    WkDateOpponentMLLineOUScoreSUATSOUHandleBetsHandleBetsHandleBets
    Nov 17 VS  Seattle
    -265
    -6
    48.5
    17-20
    L
    L
    U
    86%
    91%
    71%
    74%
    20%
    55%
    Nov 10 at  Tampa Bay
    -298
    -6.5
    50.5
    23-20
    W
    L
    U
    75%
    79%
    61%
    60%
    66%
    65%
    Oct 27 VS  Dallas
    -238
    -5.5
    47.5
    30-24
    W
    W
    O
    48%
    70%
    49%
    55%
    52%
    62%
    Oct 20 VS  Kansas City
    -142
    -2.5
    48
    18-28
    L
    L
    U
    48%
    32%
    52%
    39%
    74%
    67%
    Oct 10 at  Seattle
    -198
    -4
    49
    36-24
    W
    W
    O
    66%
    66%
    59%
    61%
    53%
    49%
    Oct 6 VS  Arizona
    -340
    -7.5
    49
    23-24
    L
    L
    U
    74%
    88%
    47%
    50%
    77%
    65%
    Sep 29 VS  New England
    -575
    -10.5
    42.5
    30-13
    W
    W
    O
    71%
    91%
    50%
    50%
    34%
    44%
    Sep 22 at  LA Rams
    -258
    -6
    44.5
    24-27
    L
    L
    O
    80%
    87%
    64%
    64%
    33%
    48%
    Sep 15 at  Minnesota
    -218
    -4.5
    46.5
    17-23
    L
    L
    U
    87%
    93%
    75%
    85%
    62%
    64%
    Sep 9 VS  NY Jets
    -192
    -3.5
    43
    32-19
    W
    W
    O
    48%
    67%
    48%
    57%
    67%
    56%

    2024 Recent Results
    BuffaloDraftKingsResultsMoney LineSpreadOVER Total
    WkDateOpponentMLLineOUScoreSUATSOUHandleBetsHandleBetsHandleBets
    Nov 17 VS  Kansas City
    -148
    -2.5
    47
    30-21
    W
    W
    O
    54%
    39%
    65%
    48%
    75%
    74%
    Nov 10 at  Indianapolis
    -230
    -4.5
    46.5
    30-20
    W
    W
    O
    89%
    92%
    63%
    81%
    81%
    66%
    Nov 3 VS  Miami
    -290
    -6.5
    49.5
    30-27
    W
    L
    O
    76%
    87%
    70%
    72%
    72%
    70%
    Oct 27 at  Seattle
    -170
    -3
    45.5
    31-10
    W
    W
    U
    80%
    80%
    76%
    77%
    72%
    81%
    Oct 20 VS  Tennessee
    -535
    -9.5
    41
    34-10
    W
    W
    O
    90%
    96%
    71%
    75%
    79%
    79%
    Oct 14 at  NY Jets
    -120
    -1
    42.5
    23-20
    W
    W
    O
    48%
    65%
    67%
    77%
    60%
    67%
    Oct 6 at  Houston
    +102
    +1.5
    48
    20-23
    L
    L
    U
    58%
    64%
    58%
    66%
    75%
    81%
    Sep 29 at  Baltimore
    +114
    +2.5
    47.5
    10-35
    L
    L
    U
    45%
    57%
    45%
    58%
    76%
    76%
    Sep 23 VS  Jacksonville
    -225
    -4.5
    46.5
    47-10
    W
    W
    O
    58%
    81%
    67%
    77%
    55%
    59%
    Sep 12 at  Miami
    +114
    +2.5
    49
    31-10
    W
    W
    U
    54%
    58%
    42%
    45%
    74%
    75%
    Sep 8 VS  Arizona
    -325
    -6.5
    46
    34-28
    W
    L
    O
    62%
    86%
    54%
    61%
    77%
    63%

    Last 5 Head to Head Results
    DateRoad/HomeScoreLineMLOUSUATSF/DH/AOU

    2020
    Dec 7
    San Francisco 49ers San Francisco 49ers
    Buffalo Bills Buffalo Bills
    24


    34
    +2.5


    -2.5
    +119


    -
    48
    BUF

     
    BUF

     
    FAV

    Over

    2016
    Oct 16
    San Francisco 49ers San Francisco 49ers
    Buffalo Bills Buffalo Bills
    16


    45
    +7.5


    -7.5
    +280


    -345
    44
    BUF

     
    BUF

     
    FAV
    HOME

     
    Over

    2012
    Oct 7
    Buffalo Bills Buffalo Bills
    San Francisco 49ers San Francisco 49ers
    3


    45
    +10


    -10
    +395


    -475
    45.5
    SFO

     
    SFO

     
    FAV
    Home

     
    Over

    2008
    Nov 30
    San Francisco 49ers San Francisco 49ers
    Buffalo Bills Buffalo Bills
    10


    3
    +6.5


    -6.5
    +270


    -290
    43
    SFO

     
    SFO

     
    DOG
    Road

     
    Under

    2004
    Dec 26
    Buffalo Bills Buffalo Bills
    San Francisco 49ers San Francisco 49ers
    41


    7
    -11


    +11
    -


    -
    42.5
    BUF

     
    BUF

     
    FAV
    Road

     
    Over



    Statistic Breakdown
    Offensive Statistics
    SFO SFOStatisticBUF BUFEdgeMargin
    10
    Games
    11
    BUF BUF
    1
    25.0
    Points Scored
    29.1
    BUF BUF
    4.1
    251.1
    Passing Yards
    226.1
    SFO SFO
    25.0
    12.4
    PYPC
    11.4
    SFO SFO
    1.1
    8.2
    PYPA
    7.3
    SFO SFO
    0.9
    66.0
    Completion PCT
    64.0
    SFO SFO
    2.0
    147.8
    Rushing Yards
    119.2
    SFO SFO
    28.6
    5.0
    RYPA
    4.3
    SFO SFO
    0.7
    49.5
    PenaltyYards
    47.0
    BUF BUF
    2.5
    1.3
    Turnovers
    0.6
    BUF BUF
    0.7
    Defensive Statistics
    SFO SFOStatisticBUF BUFEdgeMargin
    10
    Games
    11
    SFO SFO
    1
    22.2
    Points Scored
    19.5
    BUF BUF
    2.8
    197.2
    Passing Yards
    210.0
    SFO SFO
    12.8
    9.7
    PYPC
    9.0
    BUF BUF
    0.7
    6.1
    PYPA
    6.2
    SFO SFO
    0.1
    63.6
    Completion PCT
    68.9
    SFO SFO
    5.4
    105.0
    Rushing Yards
    119.1
    SFO SFO
    14.1
    4.3
    RYPA
    4.9
    SFO SFO
    0.6
    37.2
    PenaltyYards
    59.4
    BUF BUF
    22.2
    1.6
    Turnovers
    1.9
    BUF BUF
    0.3

    Statistic Breakdown
    Offensive Statistics
    SFO SFOStatisticBUF BUFEdgeMargin
    4
    Games
    5
    BUF BUF
    1
    25.0
    Points Scored
    35.0
    BUF BUF
    10.0
    293.8
    Passing Yards
    259.2
    SFO SFO
    34.6
    12.6
    PYPC
    11.3
    SFO SFO
    1.4
    9.0
    PYPA
    7.8
    SFO SFO
    1.2
    71.5
    Completion PCT
    69.3
    SFO SFO
    2.3
    135.5
    Rushing Yards
    104.8
    SFO SFO
    30.7
    4.8
    RYPA
    4.0
    SFO SFO
    0.8
    56.0
    PenaltyYards
    43.2
    BUF BUF
    12.8
    1.0
    Turnovers
    0.6
    BUF BUF
    0.4
    Defensive Statistics
    SFO SFOStatisticBUF BUFEdgeMargin
    4
    Games
    5
    SFO SFO
    1
    23.5
    Points Scored
    19.2
    BUF BUF
    4.3
    216.5
    Passing Yards
    179.6
    BUF BUF
    36.9
    10.7
    PYPC
    7.5
    BUF BUF
    3.2
    6.5
    PYPA
    5.0
    BUF BUF
    1.5
    60.9
    Completion PCT
    67.4
    SFO SFO
    6.5
    101.5
    Rushing Yards
    106.4
    SFO SFO
    4.9
    4.2
    RYPA
    4.7
    SFO SFO
    0.5
    59.8
    PenaltyYards
    48.4
    SFO SFO
    11.4
    1.3
    Turnovers
    1.6
    BUF BUF
    0.4

    Statistic Breakdown
    Offensive Statistics
    SFO SFOStatisticBUF BUFEdgeMargin
    10
    Games
    10
    -
    0
    25.0
    Points Scored
    28.6
    BUF BUF
    3.6
    251.1
    Passing Yards
    226.5
    SFO SFO
    24.6
    12.4
    PYPC
    11.3
    SFO SFO
    1.2
    8.2
    PYPA
    7.1
    SFO SFO
    1.1
    66.0
    Completion PCT
    63.0
    SFO SFO
    3.0
    147.8
    Rushing Yards
    118.1
    SFO SFO
    29.7
    5.0
    RYPA
    4.3
    SFO SFO
    0.7
    49.5
    PenaltyYards
    45.2
    BUF BUF
    4.3
    1.3
    Turnovers
    0.6
    BUF BUF
    0.7
    Defensive Statistics
    SFO SFOStatisticBUF BUFEdgeMargin
    10
    Games
    10
    -
    0
    22.2
    Points Scored
    18.6
    BUF BUF
    3.6
    197.2
    Passing Yards
    216.4
    SFO SFO
    19.2
    9.7
    PYPC
    9.2
    BUF BUF
    0.5
    6.1
    PYPA
    6.3
    SFO SFO
    0.2
    63.6
    Completion PCT
    69.0
    SFO SFO
    5.5
    105.0
    Rushing Yards
    118.6
    SFO SFO
    13.6
    4.3
    RYPA
    4.8
    SFO SFO
    0.6
    37.2
    PenaltyYards
    62.2
    BUF BUF
    25.0
    1.6
    Turnovers
    2.0
    BUF BUF
    0.4

    Statistic Breakdown
    Offensive Statistics
    SFO SFOStatisticBUF BUFEdgeMargin
    6
    Games
    6
    -
    0
    22.8
    Points Scored
    21.0
    SFO SFO
    1.8
    199.3
    Passing Yards
    205.5
    BUF BUF
    6.2
    12.0
    PYPC
    9.6
    SFO SFO
    2.4
    7.3
    PYPA
    6.0
    SFO SFO
    1.3
    61.4
    Completion PCT
    62.9
    BUF BUF
    1.6
    153.3
    Rushing Yards
    149.0
    SFO SFO
    4.3
    4.9
    RYPA
    5.5
    BUF BUF
    0.6
    37.2
    PenaltyYards
    47.8
    SFO SFO
    10.7
    1.5
    Turnovers
    2.0
    SFO SFO
    0.5