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3:30 PM ET () | Score | Line | OU | Record | ATS | O-U-P | PF | PA | EST Score | EST Line |
|---|---|---|---|---|---|---|---|---|---|---|
 Louisville (19) | 0 | +9.5 | 2-0 | 2-0-0 | 2-0-0 | 55.5 | 7.0 | 0 | 0 | |
 Notre Dame (17) | 0 | -9.5 | - | 2-1 | 2-1-0 | 1-2-0 | 34.3 | 12.0 | 0 | 0 |
| Date | Road/Home | Score | Line | ML | OU | SU | ATS | F/D | H/A | OU |
|---|---|---|---|---|---|---|---|---|---|---|
2023 Oct 7 | Notre Dame Fighting Irish Louisville Cardinals | 20 33 | -6.5 +6.5 | -258 +210 | 53.5 | LOUI | LOUI | DOG | Home | Under |
2020 Oct 17 | Louisville Cardinals Notre Dame Fighting Irish | 7 12 | +15.5 -15.5 | +477 -650 | 62 | NOTR | LOUI | DOG | Road | Under |
2019 Sep 2 | Notre Dame Fighting Irish Louisville Cardinals | 35 17 | -18.5 +18.5 | -1455 +858 | 55 | NOTR | LOUI | DOG | Home | Under |
2014 Nov 22 | Louisville Cardinals Notre Dame Fighting Irish | 31 28 | +2.5 -2.5 | +125 -145 | 51 | LOUI | LOUI | DOG | Road | Over |
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