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Monday,December 22

49ers at

Lucas Oil Stadium

8:15 PM ET (ESPN)	Score	Line	OU	Record	ATS	O-U-P	PF	PA	EST Score	EST Line
49ers	0	-3		9-4	8-5-0	7-6-0	23.6	20.7	0	0
Colts	0	+3	46.5	8-4	7-5-0	6-6-0	29.8	20.8	0	0

Head to Head Results

Date	Road/Home	Score	Line	ML	OU	SU	ATS	F/D	H/A	OU
2021 Oct 24	Indianapolis Colts San Francisco 49ers	30 18	+3.5 -3.5	+165 -190	41.5	IND	IND	DOG	Road	Over
2017 Oct 8	San Francisco 49ers Indianapolis Colts	23 26	+1 -1	+100 -120	44	IND	IND	FAV	HOME	Over
2013 Sep 22	Indianapolis Colts San Francisco 49ers	27 7	+10.5 -10.5	+390 -500	45.5	IND	IND	DOG	Road	Under
2009 Nov 1	San Francisco 49ers Indianapolis Colts	14 18	+12.5 -12.5	+575 -725	45	IND	SFO	DOG	Road	Under
2005 Oct 9	Indianapolis Colts San Francisco 49ers	28 3	-16.5 +16.5	- -	45.5	IND	IND	FAV	Road	Under
2001 Nov 25	San Francisco 49ers Indianapolis Colts	40 21	+2.5 -2.5	- -	53	SFO	SFO	DOG	Road	Over
1998 Oct 18	Indianapolis Colts San Francisco 49ers	31 34	+18 -18	- -	45	SFO	IND	DOG	Road	Over
1995 Oct 15	San Francisco 49ers Indianapolis Colts	17 18	-10.5 +10.5	- -	46.5	IND	IND	DOG	HOME	Under

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